Saturday, July 26, 2008

Oh Crap!

When under stress... My neck turns into a pretzel.

So I am currently on Baclofen. (Not my first choice) It isn't working well... full effect lasts for 2 hours and sporadic relief for 3-4 hours after that. My Dr. is unavailable until Wednesday!!!

So I look up to see the dosage increments and instructions online. Apparently my Dr. would tell me to increase by 5 Mg each day until I get the desired results or my pain/stress is gone.

I also continue to read the warnings of this drug:
(note the opposites... constipation or diarrhea, Anorexia or weight gain)
(Back pain and exacerbation of psychotic disorders?!?!?!)

Adverse Reactions

Cardiovascular

Hypotension; palpitations; chest pain.

CNS

Drowsiness; weakness in lower extremities; dizziness; seizures; headache; numbness; euphoria; depression; confusion; lethargy; insomnia; hallucinations; paresthesia; asthenia; anxiety; agitation.

Dermatologic

Pruritus; rash.

EENT

Tinnitus; blurred vision; taste disorder; nasal congestion.

GI

Nausea; vomiting; dry mouth; constipation; diarrhea; abdominal pain; anorexia.

Genitourinary

Urinary frequency; enuresis; dysuria; impotence.

Respiratory

Dyspnea; pneumonia; hypoventilation.

Miscellaneous

Hypotonia; slurred speech; muscle pain; ankle edema; excessive perspiration; weight gain; back pain.

Precautions

Warnings

Intrathecal

Abrupt discontinuation has resulted in high fever, altered mental status, exaggerated rebound spasticity, and muscle rigidity that in rare cases advances to rhabdomyolysis, multiple organ system failure and death.

Give special attention to patients at apparent risk (eg, spinal cord injuries at T-6 or above, communication difficulties, history of withdrawal symptoms from oral or intrathecal baclofen)

Epilepsy and psychotic disorders

Use with caution because of potential exacerbations.

Fatalities

Fatalities occurred in premarketing trials of intrathecal baclofen; baclofen's role in these deaths is unknown.

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